擅长儿童肿瘤及骨肿瘤靶向治疗分子机制研究

湖南省儿童医院临床儿科医学研究中心助理研究员，博士毕业于中南大学基础医学院肿瘤研究所，博士后期间从事肿瘤免疫、肿瘤表观遗传、铁死亡等肿瘤发病机制相关研究。以第一作者或通讯作者发表发表SCI论文多篇，申请并授权IKKα相关专利一项，主持湖南省青年科学基金（2022JJ40665）资助一项参与编撰《肿瘤分子生物学与细胞生物学实验手册》。 代表性论文： 1) Yan B, Guo J, Huang M, Li Z, Sun J, Tan H, Lai W, Chang S. GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC. Mediators Inflamm. 2025 Aug 18;2025:5576056. doi: 10.1155/mi/5576056. 2) Lai W; Hu W; Liang Y; Mao C; Tao T; Wang X; Xiao D; Liu S; Tao Y ; New mouse genetic model of breast cancer from IKKα defects in dendritic cells revealed by single-cell RNA sequencing, Cell Discovery, 2023, 9 3) Long, Yao; Guo, Jiaxing; Chen, Jielin; Sun, Jingyue; Wang, Haiyan; Peng, Xin; Wang, Zuli; Lai, WeiWei; Liu, Na; Shu, Long; Chen, Ling; Shi, Ying; Xiao, Desheng; Liu, Shuang; Tao, Yongguang ; GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 8(1).